therapeutic areas immuno-oncology
Immunogenicity Testing
therapeutic areas immuno-oncology

Immunogenicity Testing

neurology and neurodegenerative diseases
Ultra-Sensitive Immunoassays
Neurology biomarker testing
Biomarkers
contract research organization cell based assays
Functional Assays
antibodies
Antibody Characterization

ABL has been ranked ‘Excellent’ for ELISPOT testing with EQAPOL external quality assurance program.

ABL scored 100% on ELISPOT EQAPOL test

ABL is a contract research organization and leading global provider of immunology and biomarker analyses, offering expert laboratory & sample management services to advance promising candidates from discovery to the clinic.

55+

YEARS OF EXPERIENCE

200+

PROJECTS

50+

PARTNERS

OUR SERVICES

Whether in the discovery, preclinical or clinical stages, candidate products and therapies require robust and reliable immune monitoring tools to monitor and characterize their biological effects.
ABL’s experts can assist with:

Cell Based Assays

ELISpot
Immunophenotyping
ICS
T/B/NK Cell Enumeration
Tetramer Staining
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Immunoassay Testing

ELISA
Cytokine Profiling
ADA
Binding Affinity
and more...
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Biomarker & Cytokine Detection

Ultra-Sensitive &
Multiplexed Assays
Cytokines
Chemokines
Neurological Biomarkers
Learn More

Other ABL Specialties:

Functional Assays
Virus neutralization, ADCC, phagocytosis, cytotoxicity, proliferation, apoptosis

Molecular Virology
Virus characterization, viral load, biodistribution, qPCR/ddPCR applications

Sample Management
Sample receipt, processing, cryopreservation & distribution from whole blood, mucosal secretions & tissues

PRODUCT TYPES

ABL has successfully supported hundreds of studies evaluating the safety, immunogenicity and efficacy of biologics on behalf of our client’s preclinical and clinical programs. The breadth of our experience spans:

INDICATIONS

Immuno-Oncology

Breast cancer, Leukemia, Lymphoma, Colorectal Cancer, Glioma

Infectious Diseases

HIV, RSV, HPV, HCV, HBV, Zika, Ebola, TB, Sepsis, Typhoid, Clostridium Difficile

Neurological Disorders

Alzheimer’s, Parkinson’s, ALS, Multiple Sclerosis, Huntington's

Genetic Disorders

XLRS, CAH, Canavan Disease

Other Diseases

Crohn’s Disease, Rheumatoid Arthritis, Psoriasis, NASH, Diabetes

A QUALITY-DRIVEN APPROACH

ABL is certified according to ISO 9001:2015 standards. In addition to ISO, our Quality System is based on Good Clinical Laboratory Practices (GCLP).  

In addition to our commitment to quality, ABL is a participating member of External Proficiency programs such as EQAPOL- the External Quality Assurance Program Oversight Laboratory program and CIP- the Association for Cancer Immunotherapy (CIMT) Immunoguiding Program.  ABL is honored to be among the participating sites for evaluation of  ELISpot, Luminex and Flow Cytometry assay proficiency.

Communication

  • Project Management Oversight
  • Flexible meeting & reporting options
  • Total confidentiality
  • Timely notifications & data delivery

Technical Execution

  • Over 55 yrs of scientific expertise
  • Custom approaches based on individual study needs
  • Selection of the most relevant, state-of-the-art methods
  • Method optimization & validation available
  • Efficient execution of testing & analysis
  • Full study report

Quality

  • ISO 9001:2015
  • Secured systems
  • Stringent QC of data
  • Equipment monitoring & maintenance
  • Full traceability
  • Internal proficiency assessments

INTERNATIONAL FOOTPRINT

Wherever you are in your product development pipeline, ABL has established protocols and trained personnel for rapid study set-up at facilities located in the U.S. and Europe.

We can transfer your method to our laboratories or our team of scientists can work with you to adapt or develop a novel method. In most cases, samples can be assayed on fresh or frozen and the results provided to you in a preferred format.

Advanced BioScience Laboratories (ABL) Rockville facility

Rockville, MD, USA

Immunobiology
Biomanufacturing

Location Information

Contact us today to see how ABL can help you advance your product!