Immunology and Contract Research
When the stakes are high, scientific
guidance is life-changing
ABL is a contract research organization and leading global provider of immunology and biomarker analyses, offering expert laboratory & sample management services to advance promising candidates from discovery to the clinic.
60 years
of deep bench experience
ISO
9001:2015
Tenured
Immunologists
Your research success starts with ABL
Supporting you from the bench to the clinic
Using the methods below, ABL detects immunological responses to candidate biologics with the mission to aid our clients rapidly and efficiently advance promising concepts in support of preclinical and clinical programs.
Study design
Sample processing
Sample storage and shipment
Cellular
Humoral/
Immunoassay
Cytokines&
Biomarkers
Molecular
Report
Study design
Sample processing
Sample storage and shipment
(Immunomonitoring)
Cellular
Humoral/
Immunoassay
Cytokines&
Biomarkers
Molecular
Report
ABL offers flexible scheduling and rapid turnaround!
Contact us today!
Cell-based assays
• Custom assay development
• T and B cell ELISpot
• FluoroSpot
• Immunophenotyping
• Intracellular Cytokine Staining (ICS)
• T/B/NK Cell enumeration
• Tetramer and multimer staining
• Lymphoproliferation Study
Immunoassay testing
• ELISA
• Anti-Drug antibodies (ADA)
• Antibody affinity measurement
• Neutralizing Antibody (NAb) assays
• Antibody Dependent Cell-mediated Cytoxicity (ADCC)
• Complement Dependent Cell Cytoxicity (CDC)
• Antibody-mediated Opsonization / phagocytosis
• Epitope Mapping
Biomarker & cytokine detection
• Ultra-sensitive and multiplexed assays
• Cytokines
• Chemokines
• Neurological biomarkers
Additional ABL Specialties:
Functional Assays
- • Virus neutralization
- • ADCC/phagocytosis
- • Cytotoxicity
- • Proliferation
- • Apoptosis
Molecular Virology
- • Virus characterization
- • Viral load
- • Biodistribution
- • qPCR/ddPCR applications
Sample Management
- • Sample receipt
- • Whole blood, PBMC, serum, plasma, lymph nodes processing
- • Cells and tissues cryopreservation
Product types
Vaccines
Cell Therapies
Immunotherapies
Gene Therapies
Indications
ABL has successfully supported hundreds of studies evaluating the safety, immunogenicity and efficacy of biologics on behalf of our client’s preclinical and clinical programs. The breadth of our experience spans:
Cancer
- • Breast cancer
- • Leukemia
- • Lymphoma
- • Colorectal cancer
- • Glioma
Neurological diseases
- • Alzheimer’s
- • Parkinson’s
- • Multiple Sclerosis
- • Huntington’s
Infectious diseases
- • HIV, RSV, HPV, HCV, HBV
- • Zika, Ebola, TB
- • Sepsis, Typhoid
- • Clostridium difficile
Autoimmune diseases
- • Crohn’s disease
- • Rheumatoid arthritis
- • Psoriasis
- • NASH
- • Diabetes
Genetic and chronic disease
- • XLRS
- • CAH
- • Canavan disease
Other
- • What indication are you working with?
A quality-driven approach
ABL is certified according to ISO 9001:2015 standards.
In addition to our commitment to quality, ABL is a participating member of external proficiency programs such as EQAPOL—the External Quality Assurance Program Oversight Laboratory
ABL is honored to be among the participating sites for evaluation of ELISpot, Luminex and Flow Cytometry assay proficiency. ABL has been ranked “Excellent’ on our latest round of ELISPOT testing as part of The Duke’s Human Vaccine Institute’s EQAPOL proficiency testing.
Communication
- Project management oversight
- Flexible meeting and reporting options
- Total confidentiality
- Timely notifications and data delivery
Technical Execution
- 60 years of scientific expertise
- Custom approaches based on individual study needs
- Selection of the most relevant, state-of-the-art methods
- Method optimization and validation available
- Efficient execution of testing and analysis
- Full study report
Quality
- ISO 9001:2015
- Secured systems
- Stringent QC of data
- Equipment monitoring & maintenance
- Full traceability
- Internal proficiency assessments
Our all-in-one immunology facility
Wherever you are in your product development pipeline, ABL has established protocols and trained personnel for rapid study set-up.We can transfer your method to our laboratories or our team of scientists can work with you to adapt or develop a novel method. In most cases, fresh or frozen samples can be assayed with results provided in your preferred format.
ABL has been ranked ‘Excellent’ for ELISPOT testing with EQAPOL external quality assurance program.
