4317 – Anti-HIV-1 gp120 Env (aa 307-320)

This product is for research purposes only

Monoclonal Antibodies Safety Data Sheet

IgG is purified by affinity chromatography on Protein A Sepharose

Quantity: 100 µg

Isotype: IgG1
Immunogen: Purified native gp120 of HIV-1IIIB
Reactivity:
• Type-specific monoclonal antibody to HIV-1IIIB gp120
• Reacts with HIV-1IIIB gp120 in ELISA and immunoblots
• Inhibits syncytium formation by HIV-1-infected cells with CD4 positive uninfected cells
• Neutralizes viral infectivity by the HIV-1IIIB isolate in a type-specific manner
• Binds to the principal neutralizing determinant of HIV-1IIIB gp120 between aa307 and 320
• Use 5 µg in immunoblots

Description

Monoclonal Antibodies Safety Data Sheet

IgG is purified by affinity chromatography on Protein A Sepharose

Quantity: 100 µg

Isotype: IgG1
Immunogen: Purified native gp120 of HIV-1IIIB
Reactivity:
• Type-specific monoclonal antibody to HIV-1IIIB gp120
• Reacts with HIV-1IIIB gp120 in ELISA and immunoblots
• Inhibits syncytium formation by HIV-1-infected cells with CD4 positive uninfected cells
• Neutralizes viral infectivity by the HIV-1IIIB isolate in a type-specific manner
• Binds to the principal neutralizing determinant of HIV-1IIIB gp120 between aa307 and 320
• Use 5 µg in immunoblots

References

Reference(s): Pal, R., Veronese, F.D., Nair, B.C., Rahman, R., Hoke, G.M., Mumbauer, S.W., Gallo, R.C., and Sarngadharan, M.G. Characterization of type-specific neutralizing epitope on the external glycoprotein of HIV-1. Intervirol. 86:86-93, 1992.

Veronese, F.D., Rahman, R., Pal, R., Boyer, C., Romano, J., Kalyanaraman, V.S., Nair, B.C., Gallo, R.C., and Sarngadharan, M.G. Delineation of immunoreactive, conserved regions in the external glycoprotein of the human immunodeficiency virus type 1. AIDS Res. Hum. Retroviruses 8:1125-1132, 1992.

Determined using BCA Protein Assay (Pierce Biotechnology, Inc., Rockford, IL). ABL does not guarantee equivalent protein concentration results with other assay methods.

This product does not contain sodium azide.

Contact Us

Do not hesitate to contact us should you have any questions or enquiries.