2015 PUBLICATIONS AND PRESENTATIONS

Scientific Publications

Leung-Theung-Long S, Gouanvic M, Coupet CA, Ray A, Tupin E, Silvestre N, Marchand JB, Schmitt D, Hoffmann C, Klein M, Seegren P, Huaman MC, Cristillo AD, Inchauspé G.  A Novel MVA-Based Multiphasic Vaccine for Prevention or Treatment of Tuberculosis Induces Broad and Multifunctional Cell-Mediated Immunity in Mice and Primates. PLoS One. 2015 Nov 24;10(11):e0143552. doi: 10.1371/journal.pone.0143552. eCollection 2015. PMID: 26599077

Tuero I, Mohanram V, Musich T, Miller L, Vargas-Inchaustegui DA, Demberg T, Venzon D, Kalisz I, Kalyanaraman VS, Pal R, Ferrari MG, LaBranche C, Montefiori DC, Rao M, Vaccari M, Franchini G, Barnett SW, Robert-Guroff M. Mucosal B Cells Are Associated with Delayed SIV Acquisition in Vaccinated Female but Not Male Rhesus Macaques Following SIVmac251 Rectal Challenge. PLoS Pathog. 2015 Aug 12;11(8):e1005101. doi: 10.1371/journal.ppat.1005101. eCollection 2015 Aug. PMID: 26267144

Menon V, Sneha Priya R, Labranche C, Montefiori D, Mahalingam S, Kalyanaraman VS, Pal R. Characterization of protective immune response elicited by a trimeric envelope protein from an Indian clade C HIV-1 isolate in rhesus macaques. J Med Primatol. 2015 Jun 15. doi: 10.1111/jmp.12178. [Epub ahead of print] PMID: 26075700

García-Arriaza J, Perdiguero B, Heeney J, Seaman M, Montefiori DC, Labranche C, Yates NL, Shen X, Tomaras GD, Ferrari G, Foulds KE, McDermott A, Kao SF, Roederer M, Hawkins N, Self S, Yao J, Farrell P, Phogat S, Tartaglia J, Barnett SW, Burke B, Cristillo A, Weiss D, Lee C, Kibler K, Jacobs B, Asbach B, Wagner R, Ding S, Pantaleo G, Esteban M. Head-to-head comparison of poxvirus NYVAC and ALVAC vectors expressing identical HIV-1 clade C immunogens in prime/boost combination with Env protein in non-human primates. J Virol. 2015 Aug;89(16):8525-39. doi: 10.1128/JVI.01265-15. Epub 2015 Jun 3. PMID: 26041302

Wieczorek L, Krebs SJ, Kalyanaraman V, Whitney S, Tovanabutra S, Moscoso CG, Sanders-Buell E, Williams C, Slike B, Molnar S, Dussupt V, Alam SM, Chenine AL, Tong T, Hill EL, Liao HX, Hoelscher M, Maboko L, Zolla-Pazner S, Haynes BF, Pensiero M, McCutchan F, Malek-Salehi S, Cheng RH, Robb ML, VanCott T, Michael NL, Marovich MA, Alving CR, Matyas GR, Rao M, Polonis VR. Comparable antigenicity and immunogenicity of oligomeric forms of a novel, acute HIV-1 subtype C gp145 envelope for use in preclinical and clinical vaccine research. J Virol. 2015 Aug 1;89(15):7478-93. doi: 10.1128/JVI.00412-15. Epub 2015 May 13.

Chung HK, Pise-Masison CA, Muthiah A, Radonovich MF, Lee EM, Lee JK, Pal R.  Transcription profiling of CD4+ T cells in rhesus macaques infected with simian-human immunodeficiency virus and re-challenged with SIVmac251.  J Med Primatol. 2015 Oct;44(5):263-74. doi: 10.1111/jmp.12185. Epub 2015 Aug 31.

Shytaj IL, Nickel G, Arts E, Farrell N, Biffoni M, Pal RChung HK, LaBranche C, Montefiori D, Vargas-Inchaustegui D, Robert-Guroff M, Lewis MG, Sacha JB, Palamara AT, Savarino A.  A two-year follow-up of macaques developing intermittent control of the HIV homolog SIVmac251 in the chronic phase of the infection.  J Virol. 2015 Aug;89(15):7521-35. doi: 10.1128/JVI.00396-15. Epub 2015 May 13.

Shen X, Duffy R, Howington R, Cope A, Sadagopal S, Park H, Pal R, Kwa S, Ding S, Yang OO, Fouda GG, Le Grand R, Bolton D, Esteban M, Phogat S, Roederer M, Amara R, Picker LJ, Seder RA, McElrath MJ, Barnett S, Permar SR, Shattock R, DeVico AL, Felber BK, Pavlakis GN, Pantaleo G, Korber BT, Montefiori DC, Tomaras GD.  Vaccine-induced epitope specific antibodies to SIVmac239 envelope are distinct from those induced to the HIV-1 envelope in non-human primates.  2015 Aug 15;89(16):8643-50. doi: 10.1128/JVI.03635-14. Epub 2015 May 27.

Jain S, Trivett MT, Ayala VI, Ohlen C, Ott DE. African green monkey TRIM5α restriction in simian immunodeficiency virus-specific rhesus macaque effector CD4 T cells enhances their survival and antiviral function. J Virol. 2015 Apr;89(8):4449-56. doi: 10.1128/JVI.03598-14. Epub 2015 Feb 4. PMID: 25653448

Coren LV, Trivett MT, Jain S, Ayala VI, Del Prete GQ, Ohlen C, Ott DE. Potent restriction of HIV-1 and SIVmac239 replication by African green monkey TRIM5α. Retrovirology. 2015 Feb 7;12:11. doi: 10.1186/s12977-015-0137-9. PMID: 25809491

Fouts TR, Bagley K, Prado IJ, Bobb KL, Schwartz JA, Xu R, Zagursky RJ, Egan MA, Eldridge JH, LaBranche CC, Montefiori DC, Le Buanec H, Zagury D, Pal R, Pavlakis GN, Felber BK, Franchini G, Gordon S, Vaccari M, Lewis GK, DeVico AL, Gallo RC. Balance of cellular and humoral immunity determines the level of protection by HIV vaccines in rhesus macaque models of HIV infection. Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):E992-9. doi: 10.1073/pnas.1423669112. Epub 2015 Feb 13.

Sneha Priya R, Veena M, Kalisz I, Whitney S, Priyanka D, LaBranche CC, Sri Teja M, Montefiori DC, Pal R, Mahalingam S, Kalyanaraman VS. Antigenicity and Immunogenicity of a Trimeric Envelope protein from an Indian clade C HIV-1 isolate. J Biol Chem 290:9195-208, 2015.

Vargas-Inchaustegui DA, Xiao P, Demberg T, Pal R, Robert-Guroff M. Therapeutic envelope vaccination in combination with antiretroviral therapy temporarily rescues SIV-specific CD4+ T cell-dependent NK cell effector responses in chronically infected rhesus macaques. Immunology 145:288-99, 2015.

Asmal M, Luedemann C, Lavine CL, Mach LV, Balachandran H, Brinkley C, Denny TN, Lewis MG, Anderson H, Pal R, Sok D, Le K, Pauthner M, Hahn BH, Shaw GM, Seaman MS, Letvin NL, Burton DR, Sodroski JG, Haynes BF, Santra S. Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes. Virology. 2015 Jan 15;475:37-45. doi: 10.1016/j.virol.2014.10.032. Epub 2014 Nov 22. PMID: 25462344

Presentations/Abstracts

Lowry A, Turpin J, Veronese F, Cummins J, Pal R, Richardson-Harman N, Spreen W, Yueh YL, Ford S. Correlation of the Protective Cabotegravir Plasma Concentration and In vivo Efficacy.  Conference on Retroviruses and Opportunistic Infections (CROI), Seattle, WA, February 23-26, 2015.

Leung-Theung-Long, M. Gouanvic, CA. Coupet, A. Ray, N. Silvestre, JB. Marchand, D. Schmitt, C. Hoffmann, M. Klein, P. Seegren, M.C. Huaman, A.D. Cristillo, P. Ancian, EL Nuermberger, K. Mdluli, G. Inchauspé. A Novel Mva Based Post-Exposure Multiphasic Vaccine To Improve Treatment Of Active Tuberculosis. 4th Global Forum on TB Vaccines, Shangai, Japan, April 21-24, 2015.

Leung-Theung-Long, M. Gouanvic, CA. Coupet, A. Ray, N. Silvestre, JB. Marchand, D. Schmitt, C. Hoffmann, M. Klein, P. Seegren, M.C. Huaman, A.D. Cristillo, P. Ancian, EL Nuermberger, K. Mdluli, G. Inchauspé. A Novel Mva Based Post-Exposure Multiphasic Vaccine To Improve Treatment Of Active Tuberculosis. Keystone, Santa Fe, New Mexico, Jan 22-27, 2015.

S. Leung-Theung-Long, M. Gouanvic, CA. Coupet, A. Ray, N. Silvestre, JB. Marchand, D. Schmitt, C. Hoffmann, M. Klein, P. Seegren, M.C. Huaman, A.D. Cristillo, P. Ancian, EL Nuermberger, K. Mdluli, G. Inchauspé. A Novel Mva Based Post-Exposure Multiphasic Vaccine To Improve Treatment Of Active Tuberculosis.  Société Française d’Immunologie, Paris, France, Jan 21-23.