2012 Publications and Presentations

Scientific Publications

Buonaguro L, Tagliamonte M, Visciano ML, Andersen H, Lewis M, Pal R, Tornesello ML, Schroeder U, Hinkula J, Wahren B, Buonaguro FM.  Immunogenicity of HIV virus-like particles in rhesus macaques by intranasal administration.  Clin Vaccine Immunol 19:970-3, 2012.

Casu F, Harston RK, Chiacchio M, Gumina G.  Synthesis of 2’ substituted inosine analogs via unusual masking of the 6-hydroxyl group.  Nucleosides, Nucleotides and Nucleic Acids 31:224-35, 2012.

Cox JH, Ferrari MG, Earl P, Lane JR, Jagodzinski LL, Polonis VR, Kuta EG, Boyer JD, Ratto-Kim S, Eller LA, Pham DT, Hart L, Montefiori D, Ferrari G, Parrish S, Weiner DB, Moss B, Kim JH, Birx D, VanCott TC. Inclusion of a CRF01_AE HIV envelope protein boost with a DNA/MVA prime-boost vaccine; impact on humoral and cellular immunogenicity and viral load reduction after SHIV-E challenge. Vaccine 30:1830-40, 2012.

Demberg T, Brocca-Cofano E, Xiao P, Venzon D, Vargas-Inchaustegui D, Lee EM, Kalisz I, Kalyanaraman VS, Dipasquale J, McKinnon K, Robert-Guroff M. Dynamics of memory B-cell populations in blood, lymph nodes, and bone marrow during antiretroviral therapy and envelope boosting in simian immunodeficiency virus SIVmac251-infected rhesus macaques. J Virol. 2012 Dec;86(23):12591-604. doi: 10.1128/JVI.00298-12. Epub 2012 Sep 12.

Pal R, Galmin L, Lara P, Li B, Zhang J, Li D, Francis J, McNicholl J, Weiss D, Smith J.  Virological and molecular characterization of a simian human immunodeficiency virus (SHIV) encoding the envelope and reverse transcriptase genes from HIV-1.  Virology 432:173-83, 2012.

Patterson LJ, Kuate S, Daltabuit-Test M, Li Q, Xiao P, McKinnon K, DiPasquale J, Cristillo A, Haase A, Robert-Guroff M. Replicating adenovirus-simian immunodeficiency virus (SIV) vectors efficiently prime SIV-specific systemic and mucosal immune responses by targeting myeloid dendritic cells and persisting in rectal macrophages, regardless of immunization route. Clin Vaccine Immunol 19:629-37, 2012.

Pegu, P, Vaccari, M, Gordon, S, Keele, B, Doster, M, Guan, YJ, Ferrari, G, Pal, R, Ferrari, M, Whitney, S, Hudacik, L, Billings, E, Rao, M, Montefiori, D, Tomaras, G, Alam, M, Fenizia, C, Lifson, ZJ, Stablein, D, Tartaglia, J, Michael, N, Kim, J, Venzon, D, Franchini, G.  Antibodies with high avidity to the gp120 envelope protein in protection from SIVmac251 acquisition in an immunization regimen that mimics the RV-144 Thai Trial.  J Virol (in press).

Xiao P, Patterson LJ, Kuate S, Brocca-Cofano E, Thomas MA, Venzon D, Zhao J, DiPasquale J, Fenizia C, Lee EM, Kalisz I, Kalyanaraman VS, Pal R, Montefiori D, Keele BF, Robert-Guroff, M.  Replicating adenovirus-simian immunodeficiency virus (SIV) recombinant priming and envelope protein boosting elicits localized, mucosal IgA immunity in rhesus macaques correlated with delayed acquisition following a repeated low dose rectal SIVmac251 challenge.  J Virol 86:4644-57, 2012.


Chung, HK, Firpo, P, Pal, R, Hu, S-L, Pincus, SH.  SHIV-infected macaques as a model of viral latency and activation.  30th Annual Symposium on Nonhuman Primate Models for AIDS.  San Antonio, TX.  October 24-28, 2012.

Chung, HK, Firpo, P, Pal, R, Hu, S-L, Pincus, SH.  SHIV-infected macaques as a model of viral latency and activation.  Strategies for an HIV Cure.  Washington DC.  November 28-30, 2012.

Cristillo, A.  Increased antibody breadth in lupus rabbits immunized with an envelope-based HIV-1 DNA prime/protein boost vaccine.  International Conference of Clinical and Cellular Immunology.  Chicago, IL.  October 22-24, 2012.

Menon, V, Whitney S, Francis J, Ajayi, L, Petrovsky, N, Montefiori, DC, Pal, R, Kalyanaraman, VS.  Characterization in rabbits and nonhuman primates of the neutralizing antibody response elicited by DNA and protein vaccination with SIVmac251 and SIVsmE660 oligomeric envelopes.  AIDS Vaccine 2012.  Boston, MA.  September 9-12, 2012.

Pincus, SH, Valentine, M, Vitetta, ES, Chung, HK, Robinson, JE, Firpo, P, Hu, S-L.  Eradication of latent HIV reservoirs with antibodies and immunoconjugates.  Strategies for an HIV Cure.  Washington, DC.  November 28-30, 2012.